Immunoglobulins Associated With Human Platelets

Immunoglobulins associated with human platelets.

Release of serotonin from human platelets induced by aggregated immunoglobulins of different classes and subclasses.

The ability of human myeloma proteins of different classes and subclasses and of macroglobulins (all aggregated with bis-diazotized benzidine or heat) to aggregate washed human platelets and release [(3)H]-serotonin from the platelets was investigated and compared with the activity of normal IgG and tetanus-antitetanus IgG antigen-antibody complexes. Aggregated IgG1, IgG2, IgG3, IgG4, and norma...

9 Human Immunoglobulins

9.5 Range of Application, Dosage 9.5.1 Indications for Subcutaneous or Intramuscular Injection of Normal Immunoglobulins 9.5.2 Indications for Intravenous Injection of Normal Immunoglobulins 9.5.2.1 Primary Immunodeficiency Diseases 9.5.2.2 Secondary Immunodeficiency Diseases 9.5.2.3 High-Dose ivIg Treatment in Certain Autoimmune Diseases and Diseases of Unknown Etiology 9.5.3 Licensed Indicati...

9 Human Immunoglobulins

9.5 Range of Application, Dosage 9.5.1 Indications for Subcutaneous or Intramuscular Injection of Normal Immunoglobulins 9.5.2 Indications for Intravenous Injection of Normal Immunoglobulins 9.5.2.1 Primary Immunodeficiency Diseases 9.5.2.2 Secondary Immunodeficiency Diseases 9.5.2.3 High-Dose ivIg Treatment in Certain Autoimmune Diseases and Diseases of Unknown Etiology 9.5.3 Licensed Indicati...

Potatoes: Source of Laboratory Reagent for Human Platelets Research

Irish potatoes is rich in carbohydrate, with varied glucose levels. It is also a very good source of apyrase, an enzyme used for platelet storage. The aim of this study was to explore Irish potatoes as an easily available source for apyrase extraction and purification. Apyrase was extracted from 5 Kg of Irish potatoes. Platelets were derived from 5-10 ml of human whole blood and G6PD activity w...